George Cooper, Antoni Sarcevic, and Conor Grant scored as Morecambe had Ritchie Sutton sent off.
“I am pleased because we did a professional job, the mentality of the players was spot on,” Lowe said.
The turning point of the game came when Sutton was dismissed for a foul on goal-bound Dom Telford and Cooper swept in the 20-yard free-kick.
Sarcevic made it 2-0 from a first-half stoppage time penalty and substitute Grant wrapped up the result with the last kick of the game.
“Once we got the free-kick and the penalty we were away. Then we got the goal late on as well. They were always going to sit back in. The possession stats show we had 73 percent and it’s hard when there is a man sent off,” Lowe also added.
“For us the way we moved the ball around, with tempo, quick, fast and two wing-backs high up the pitch we knew we were going to cause any team we played a problem.
“Credit to the boys mentally they were at it as well because it’s tough when you are playing bottom of the league and expected to win three-four or five-nil.
“Listen we got three goals and a clean sheet, another win, and I am pleased. With all due respect to Morecambe, we knew we could get at them. The overall play from back to front was very good.”
Morecambe’s former Argyle boss Derek Adams said: “The change in the game was the sending off. We were really in the game at that stage and we didn’t have any trouble.
“They had a lot of corner kicks and shots, but a lot of those were off target and we limited them to very few opportunities on goal.
“They had to score with a well-taken free-kick, and then we gave a penalty away just before half-time.
“They scored (their third) with the last kick of the game when we had played the whole of the second half with 10 men.
“What I will say is that I am very proud of my players, the way they stuck at it. It is not easy to come to Home Park against a team that think they should be higher up the league.
“We limited them to few chances and pressed them high up the pitch and didn’t let them play out from the back.
“That caused them problems because they gave the ball away. We could have got a goal when the big center-half loses the ball and AJ nearly gets in. And then in the second half, Lewis Alessandra has a really good chance.”